Commissioner Lalit Modi is considering plans to stage two Indian Premier League tournaments a year - one in India and another shorter one overseas.
The IPL was forced to move this year because of security concerns in India.
But the event in South Africa has been so well received that Modi is exploring the possibility of taking the game into untapped markets across the globe.
"The IPL will be based in India but a second season will help us see if a market exists elsewhere too," he said.
"The potential is huge. We have turned the challenges and adversities in moving to South Africa into an opportunity. It is fans who determine if you are successful or not and they have come out in force here.
"It has shown that the tournament can be in any region, in any country. This opens up many different opportunities for us."
The USA, where the ICC has advised cricket officials to install an IPL-style Twenty20 league, is one of the countries Modi is considering as a potential host.
"America throws up challenges but the format we have developed works. That will work anywhere," the IPL commissioner told the Daily Telegraph.
Modi also revealed he could yet take the tournament to England after they were overlooked in favour of South Africa to stage this year's event.
"Before this tournament we did not know if we could do it," Modi added. "But we do know now. We have to satisfy an appetite across the world and build a fan base across the world.
"We will talk to the England and Wales Cricket Board, and South Africa are natural allies who want us to come back every year.
"The public and the boards want us but it is not realistic to come back to the same place every year."
The rise of Twenty20 is set to continue with the launch of tournaments in England, and another event involving players from Australia, New Zealand and South Africa.